The collection of these publications is made possible thanks to the group "Scientific studies: VACCINES • COVID-19 • SARS-CoV-2"
Myocarditis after COVID-19 BNT162b2 vaccination among Hong Kong adolescents
Xue Li, PhD; Francisco Tsz Tsun Lai, PhD; Gilbert T. Chua, MBBS; et al Mike Yat Wah Kwan, MSc; Yu Lung Lau, MD; Patrick Ip, MPH, MBBS; Ian Chi Kei Wong, PhD
JAMA Pediatr. Published online February 25, 2022. doi: 10.1001 / jamapediatrics.2022.010
"A total of 224 560 first doses and 162 518 second doses of BNT162b2 were administered to adolescents. Forty-three adolescents had myocarditis-related hospitalization after receiving the BNT162b2 vaccination."
Myocarditis and Pericarditis After COVID-19 Vaccination: Inequalities in Age and Vaccine Types
Minghui Li, Jing Yuan, Gang Lv, Jacob Brown, Xiangxiang Jiang and Zhiqiang Kevin Lu
J. Pers. Med. 2021, 11 (11), 1106; https://doi.org/10.3390/jpm11111106
"An increasing number of myocarditis / pericarditis incidences have been reported following vaccination against coronavirus disease-19 (COVID-19) in adolescents and young adults."
COVID 19 vaccine for adolescents. Concern for myocarditis and pericarditis
Giuseppe Calcaterra, Jawahar Lal Mehta [ORCID], Cesare de Gregorio [ORCID], Gianfranco Butera, Paola Neroni, Vassilios Fanos and Pier Paolo Bassareo
Pediatr. Rep. 2021, 13 (3), 530-533; https://doi.org/10.3390/pediatric13030061
"There has recently been an alarming onset of some cases of myocarditis and pericarditis following the administration of Pfizer-BioNTech and Moderna COVID-19 mRNA-based vaccines in male adolescents"
Myocarditis and pericarditis after vaccination for COVID-19
George A. Diaz, MD1; Guilford T. Parsons, MD, MS2; Sara K. Gering, BS, BSN3; et al
JAMA. 2021;326(12):1210-1212. doi: 10.1001 / pit.2021.13443
"Some vaccines are associated with myocarditis, including mRNA vaccines, and the Centers for Disease Control and Prevention recently reported a possible association between COVID-19 mRNA vaccines and myocarditis, mainly in younger male individuals within days after the second vaccination. , with an incidence of approximately 4,8 in 1 million cases.6 This study shows a similar pattern, albeit with a higher incidence, suggesting insufficient reporting of vaccine adverse events. In addition, pericarditis may be more common. of myocarditis among older patients. "
Vaccination-Associated Myocarditis SARS-CoV-2 mRNA in Children Aged 12-17: A Stratified Analysis of the National Database
Beth Høeg, Allison Krug, Josh Stevenson, John Mandrola
"Post-vaccination CAE rate was higher in 12-15 year old boys after the second dose. For 12-17 year old boys with no medical comorbidities, the probability of post vaccination CAE is 162,2 and 93 for million"
Myocarditis after immunization with COVID-19 mRNA vaccines in members of the US military
Jay Montgomery, MD; Margaret Ryan, MD, MPH; Renata Engler, MD; et al
JAMA Cardiol. 2021;6(10):1202-1206. doi: 10.1001 / jamacardio.2021.2833
"A total of 23 male patients (22 currently serving in the military and 1 retired; median age [range], 25 [20-51] years) presented with acute onset of severe chest pain within 4 days of receiving a COVID-19 mRNA vaccine. All military members were previously healthy with a high level of fitness. "
COVID-19 Vaccination-associated myocarditis in adolescents
Supriya S. Jain, MD; Jeremy M. Steele, MD; Brian Fonseca, MD; Sihong Huang, MD, MMsc; Sanket Shah, MD; Shiraz A. Maskatia, MD; Sujatha Buddhe, MD, MS; Nilanjana Misra, MBBS; Preeti Ramachandran, MD; Lasya Gaur, MD; Parham Eshtehardi, MD; Shafkat Anwar, MD; Neeru Kaushik, MD; Frank Han, MD; Nita Ray Chaudhuri, MD; Lars Grosse-Wortmann, MD
Pediatrics (2021) 148 (5): e2021053427. https://doi.org/10.1542/peds.2021-053427
"We included 63 patients with a mean age of 15,6 years; 92% were male. All had received a messenger RNA vaccine and, except one, presented after the second dose."
Cardiac inflammation after COVID-19 mRNA vaccines: A comprehensive pharmacovigilance analysis
Laurent Chouchana, View ORCID ProfileAlice Blet, View ORCID ProfileMohammad Al-Khalaf, Tahir S. Kafil, Girish Nair, View ORCID ProfileJames Robblee, View ORCID ProfileMilou-Daniel Drici, View ORCID ProfileMarie-Blanche Valnet-Rabier, Joëlle Micallef, View ORCID Salvo, View ORCID ProfileJean-Marc Treluyer, Peter P. Liu
"Inflammatory reactions of the heart, i.e. myocarditis and pericarditis, have been reported worldwide shortly after COVID-19 mRNA vaccination. An important disproportionate reporting among adolescents and young adults, particularly in males, has been observed. especially for myocarditis. "
Myocarditis with COVID-19 mRNA vaccines
Biykem Bozkurt, Ishan Kamat and Peter J. Hotez
Originally published 20 Jul 2021 - https://doi.org/10.1161/CIRCULATIONAHA.121.056135 - Circulation. 2021; 144: 471–484
"According to the US Centers for Disease Control and Prevention, myocarditis / pericarditis rates are ≈12,6 cases per million mRNA vaccine doses."
Myocarditis after Covid-19 vaccination in a large health organization
Guy Witberg, MD, Noam Barda, MD, Ph.D., Sara Hoss, MD, Ilan Richter, MD, MPH, Maya Wiessman, MD, Yaron Aviv, MD, Tzlil Grinberg, MD, Oren Auster, M.Sc., Noa Dagan, MD, Ph.D., MPH, Ran D. Balicer, MD, Ph.D., MPH, and Ran Kornowski, MD
December 2, 2021 - N Engl J Med 2021; 385: 2132-2139 - DOI: 10.1056 / NEJMoa2110737
"Among patients in a large Israeli healthcare system who received at least one dose of the BNT162b2 mRNA vaccine, the estimated incidence of myocarditis was 2,13 cases per 100.000 people; the highest incidence was among male patients aged between 16 and 29 years. "
Myocarditis after the BNT162b2 mRNA vaccine against Covid-19 in Israel
Dror Mevorach, MD, Emilia Anis, MD, MPH, Noa Cedar, MPH, Michal Bromberg, MD, MPH, Eric J. Haas, MD, MSCE, Eyal Nadir, MD, Sharon Olsha-Castell, MD, Dana Arad, RN, MSN, Tal Hasin, MD, Nir Levi, MD, Rabea Asleh, MD, Ph.D., Offer Amir, MD, Karen Meir, MD, Dotan Cohen, MD, Rita Dichtiar, MPH, Deborah Novick, M.Sc., Yael Hershkovitz, M.Sc., Ron Dagan, MD, Iris Leitersdorf, MD, MHA, Ronen Ben-Ami, MD, Ian Miskin, MD, Walid Saliba, MD, MPH, Khitam Muhsen, Ph.D., Yehezkel Levi, MD, Manfred S. Green, MB, Ch.B., Ph.D., Lital Keinan-Boker, MD, Ph.D., and Sharon Alroy-Preis, MD, MPH
December 2, 2021 - N Engl J Med 2021; 385: 2140-2149 - DOI: 10.1056 / NEJMoa2109730
"The incidence of myocarditis, although low, increased after receipt of the BNT162b2 vaccine, particularly after the second dose among young males. The clinical presentation of myocarditis after vaccination was usually mild."
Safety of the BNT162b2 mRNA Covid-19 vaccine in a national context
Noam Barda, MD, Noa Dagan, MD, Yatir Ben-Shlomo, B.Sc., Eldad Kepten, Ph.D., Jacob Waxman, MD, Reut Ohana, M.Sc., Miguel A. Hernán, MD, Marc Lipsitch , D. Phil., Isaac Kohane, MD, Doron Netzer, MD, Ben Y. Reis, Ph.D., and Ran D. Balicer, MD
September 16, 2021 - N Engl J Med 2021; 385: 1078-1090 - DOI: 10.1056 / NEJMoa2110475
"The vaccine has been associated with an excessive risk of myocarditis (1 to 5 events per 100.000 people). The risk of this potentially serious adverse event and many other serious adverse events was substantially increased following SARS-CoV infection. -2"
Sudden Myocarditis-Induced Death After BNT162b2 mRNA COVID-19 Vaccination in Korea: Case Report Focused on Histopathological Findings
Sangjoon Choi, SangHan Lee, Jeong-Wook Seo, Min-ju Kim, Yo Han Jeon, Ji Hyun Park, Jong Kyu Lee, and Nam Seok Yeo
J Korean Med Sci. 2021 Oct 18; 36 (40): e286. English. - Published online Jul 10, 2021. https://doi.org/10.3346/jkms.2021.36.e286
"This unique case provides an example of a serious adverse event following COVID-19 mRNA vaccination. It is not known whether this case is related to the type of vaccine or to a specific component of the vaccine."
Myocarditis after COVID-19 mRNA vaccines
T Koizumi, T Awaya, K Yoshioka, S Kitano, H Hayama, K Amemiya, Y Enomoto, Y Yazaki, M Moroi, M Nakamura
QJM: An International Journal of Medicine, Volume 114, Issue 10, October 2021, Pages 741–743, https://doi.org/10.1093/qjmed/hcab244 - Published: 21 September 2021
"Therefore, post-vaccination myocarditis is also suggested to be associated with autoimmunity and allergies, while reports of herpes zoster after vaccination suggest a temporary decrease in cellular immunity."
Acute myocardial infarction and myocarditis after COVID-19 vaccination
YN Aye, AS Mai, A Zhang, OZH Lim, N Lin, CH Ng, MY Chan, J Yip, P -H Loh, NWS Chew
QJM: An International Journal of Medicine, hcab252, https://doi.org/10.1093/qjmed/hcab252 - Published: 29 September 2021
"Most were men and myocarditis patients were younger than those with AMI. Myocarditis patients tended to present 72 hours after vaccination, while AMI patients were older and typically presented 24 hours after vaccination. Most patients with AMI or myocarditis developed symptoms after the first and second vaccination doses, respectively. "
Myocarditis after COVID-19 vaccination - A case series
Dan Levina, Gil Shimona, Maggie Fadlon-Deraia, Liron Gershovitza, Amiram Shovalia, Anat Sebbaga, Shakib Badera, Noam Finka, Barak Gordonab
Vaccine Volume 39, Issue 42, 8 October 2021, Pages 6195-6200
"Recent studies have reported myocarditis events after COVID-19 vaccination. Marshall and colleagues described 7 cases of myocarditis in adolescents within 4 days of the second dose of the Pfizer-BioNTech COVID-19 vaccine."
Association of myocarditis with the COVID-162 messenger RNA vaccine BNT2b19 in a series of cases of children
Audrey Dionne, MD; Francesca Sperotto, MD; Stephanie Chamberlain et al
JAMA Cardiol. 2021;6(12):1446-1450. doi: 10.1001 / jamacardio.2021.3471
"Fifteen patients were admitted to the Department of Cardiology, Boston Children's Hospital for the management of myocarditis after COVID-19 vaccination between May 1 and July 15, 2021. The median age was 15 years (range, 12-18 years). , and most of the patients were male (n = 14 [93%]). "
Myocarditis and pericarditis in association with COVID-19 mRNA vaccination: cases from a regional pharmacovigilance center
Ioanna Istampoulouoglou, Georgios Dimitriou, Selina Späni, Andreas Christ, Barbara Zimmermanns, Sarah Koechlin, Oliver Stoeckmann, Clemens Winterhalder, David Marono, Valeriu Toma, Anne B Leuppi-Taegtmeyer
"Seventeen cases were reported between March and July 2021. Of these, nine had perymyocarditis, five had myocarditis and three had pericarditis. Twelve patients were male (71%). The median age was 38 years (range 17 - 88). The most commonly observed presenting symptom was acute chest pain (65%). While 47% of patients were previously healthy, 53% had at least one pre-existing comorbidity, with hypertension being the most prevalent (24%). "
Trends in outpatient cardiac consultations for suspected myocarditis after COVID-19 vaccination
Holger Eggebrecht, Philipp Breitbart, Alexander Koch, Bernd Nowak, Claudia Walther, Thomas Voigtländer, Christoph Liebetrau, Rajendra H. Metha & Axel Schmermund
Clinical Research in Cardiology volume 111, pages 237–239 (2022)
Clinical presentation and outcomes of post-vaccination mRNA myocarditis: A meta-analysis and systematic review
Abhishek Matta, Rajesh Kunadharaju, Marcus Osman, Christy Jesme, Zachary McMiller, Erika M. Johnson, Danielle Matta, Rekha Kallamadi, Dinesh Bande
Published: November 03, 2021 - DOI: 10.7759 / cureus.19240
"For the 69 patients included in our study, the median age was 21 years, from 14 to 70 years; 92,7% were male and 7,3% were female. 76,8% of patients received Pfizer-BioNTech vaccine, and the rest of 23,2% received Moderna vaccine. 11,5% of patients developed symptoms after the first dose, and 88,5% developed symptoms after the second dose . 81,2% reported no significant medical history in the past. 8,7% of included patients had a previous COVID-19 infection. Among patients with a history of COVID-19 infection, the 50% developed myocarditis after the first dose of the vaccine. "
Cases of myocarditis reported after mRNA-based COVID-19 vaccination in the United States from December 2020 to August 2021
Matthew E. Oster, MD, MPH; David K. Shay, MD, MPH; John R. Su, MD, PhD, MPH et al
JAMA. 2022;327(4):331-340. doi: 10.1001 / pit.2021.24110
"Between December 14, 2020 and August 31, 2021, 192.405.448 individuals over 12 years of age received a total of 354 100 845 mRNA-based COVID-19 vaccines. VAERS received 1991 reports of myocarditis (391 of which also included pericarditis) after receiving at least 1 dose of COVID-19 mRNA vaccine (eTable 1 in the supplement) and 684 reports of pericarditis without the presence of myocarditis. "