In the study "Hepatitis B vaccine and the risk of CNS inflammatory demyelination in childhood" (year 2008), the correlation between the Engerix B vaccine administered in childhood and the onset of multiple sclerosis is denied. However, a doubt is raised, hoping for further future studies that would confirm / deny the correlation. Those "future studies" have never been carried out. However, the correlation between vaccines for hepatitis B and the onset of numerous demyelinating pathologies is confirmed by other studies (multiple sclerosis is a demyelinating pathology).
Background: The risk of CNS inflammatory demyelination associated with the hepatitis B (HB) vaccine is discussed, with studies reporting conflicting results.
Methods: We conducted a population-based case-control study in which the cases were children with a first episode of acute inflammatory demyelination of the CNS in France (1994-2003). Each case was matched by age, gender and geographical position to a maximum of 12 controls, randomly chosen by the general population. Vaccination information was confirmed by a copy of the vaccination certificate. The probability ratios (OR) of CNS inflammatory demyelination associated with HB vaccination were estimated using conditional logistic regression.
Results: HB vaccination rates in the 3 years preceding the index date were 24,4% for 349 cases and 27,3% for their 2.941 corresponding checks. Vaccination against HB during this period was not associated with an increase in the rate of inflammatory demyelination of the CNS (adjusted OR, 0,74; 0,54-1,02), neither> 3 years nor as a function of the number of injections or brand type. When the analysis was limited to vaccine-compliant subjects, exposure to the HB vaccine> 3 years before the index date was associated with an increase in trend (1,50; 0,93–2,43), essentially from Engerix B vaccine (1,74; 1,03–2,95). OR was particularly high for this brand in patients with confirmed multiple sclerosis (2,77; 1,23–6,24).
Conclusions: vaccination against hepatitis B generally does not increase the risk of inflammatory demyelination of the CNS in childhood.
However, the Engerix B vaccine appears to increase this risk, particularly for confirmed, long-term multiple sclerosis.
Our results require confirmation in future studies.
NB: this correlation is admitted ambiguously also by WHO:
"Three possible theories explain the link between MS and hepatitis B vaccine: 1) coincidence, due to the large number of hepatitis B vaccine doses administered, many to individuals in the age groups in which MS first occurs; 2) "triggering", an increased risk of demyelination following hepatitis B vaccine that would act as a "trigger" in individuals predisposed to develop MS or other central nervous system demyelinating disease; and 3) a true causal association between hepatitis B vaccination and MS or other demyelinating disease. "
"Three possible theories explain the link between MS and the hepatitis B vaccine: 1) coincidence, due to the large number of doses of hepatitis B vaccine administered, many to people in the age groups in which the SM; 2) "trigger" means an increased risk of demyelination following the hepatitis B vaccine which would act as a "trigger" in subjects predisposed to develop MS or other demyelinating diseases of the central nervous system; and 3) a true causal association between vaccination against hepatitis B and MS or other demyelinating disease ".
"Trigger" or "no trigger" is all too evident that the association exists, despite the fact that hundreds of junk studies have been published aimed at denying this connection.
The predisposition can also be induced..by the vaccine itself!
This is just another of the vaccines that is also spreading horrible autoimmune diseases in childhood and adulthood.
ADEM = disseminated acute encephalomyelitis; BCG = Bacillo Calmette-Guèrin; HB = hepatitis B; MS = multiple sclerosis; OR = odds ratio.